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法洛四联症完全修复术后的窦房结功能与传导系统

Sinus node function and conduction system after complete repair of tetralogy of Fallot.

作者信息

Niederhauser H, Simonin P, Friedli B

出版信息

Circulation. 1975 Aug;52(2):214-20. doi: 10.1161/01.cir.52.2.214.

Abstract

Twenty-three children underwent electrophysiological studies during routine postoperative catheterization two months to five years after complete correction of tetralogy of Fallot. The aim of the study was to investigate the whole conduction system, including sinus node function, suing His bundle recordings and atrial pacing. H-V intervals were normal at rest and with pacing in twenty-two patients, including four patients with evidence of bifascicular block on the surface ECG. One patient with cardiomegaly and evidence of diffuse myocardial damage had a prolonged H-V interval but did not develop a block at this level during pacing A-H interval was slightly prolonged in four patients and normal in all others. The threshold of pacing-induced atrioventricular block ranged from 75 to 240/min and was somewhat age dependent (r = -0.55). Two patients fell below the 95% confidence limit of this regression and are considered abnormal. One returned to normal after intravenous injectionof atropine. Corrected sinus node recovery time ranged from 60 to 2000 msec. Three patients had values above 500 msec which are considered abnormal. These patients had other minor signs of sinus node dysfunction, i.e., episodes of sino-atrial block at rest or intermittent sinus bradycardia. Thus, while the His Purkinje system performed satisfactorily in all patients, sinus node dysfunctional and A-V node dysfunction were demonstrated in a few patients after correction of tetralogy of Fallot.

摘要

23名儿童在法洛四联症完全矫正术后2个月至5年进行常规术后导管检查时接受了电生理研究。该研究的目的是通过希氏束记录和心房起搏来研究整个传导系统,包括窦房结功能。22例患者静息和起搏时H-V间期正常,其中4例体表心电图有双分支阻滞证据。1例有心脏扩大和弥漫性心肌损伤证据的患者H-V间期延长,但起搏时未在该水平发生阻滞。4例患者A-H间期轻度延长,其他患者均正常。起搏诱发房室阻滞的阈值为75至240次/分钟,且与年龄有一定相关性(r = -0.55)。2例患者低于该回归曲线的95%置信限,被认为异常。1例静脉注射阿托品后恢复正常。校正窦房结恢复时间为60至2000毫秒。3例患者的值高于500毫秒,被认为异常。这些患者有其他轻微的窦房结功能障碍迹象,即静息时窦性停搏或间歇性窦性心动过缓发作。因此,虽然所有患者的希氏-浦肯野系统功能良好,但法洛四联症矫正术后仍有少数患者出现窦房结功能障碍和房室结功能障碍。

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