Ottó S
Országos Onkológiai Intézet, Budapest.
Orv Hetil. 2001 Jul 22;142(29):1541-5.
The author describes new varieties of fecal occult blood screening strategies in respect to old and up-to-date diagnostic methods. The limited sensitivity and specificity of the classical methods used for the demonstration of occult fecal blood necessitate the introduction of new techniques in the screening practice. The new discoveries in molecular biology are likely to improve the effectiveness of the early detection of colorectal cancers and their precursor lesions. Since the implementation of these novel techniques in mass screenings has not taken place yet, higher effectiveness can only be achieved by more specific and sensitive blood tests.
作者针对旧的和最新的诊断方法描述了粪便潜血筛查策略的新种类。用于检测粪便潜血的传统方法灵敏度和特异性有限，因此有必要在筛查实践中引入新技术。分子生物学的新发现可能会提高结直肠癌及其前驱病变早期检测的有效性。由于这些新技术尚未在大规模筛查中应用，只有通过更特异、更灵敏的血液检测才能实现更高的有效性。
