Comparative study on the use of co-trimoxazole and tetracycline in the treatment of lower respiratory tract infections.
作者信息
Sallam M A, Sallam I A
出版信息
Curr Med Res Opin. 1975;3(4):229-31. doi: 10.1185/03007997509113677.
PMID:1149490
Abstract
A double-blind trial was carried out on 116 patients with lower respiratory tract infection and systemic manifestations. One group received co-trimoxazole (480 mg. trimethoprim and 2,400 mg. sulphamethoxazole daily), and the other group received 2 g. tetracycline daily. The trial, as judged by clinical improvements, the reduction of purulent sputum and the rate of eradication of infection, showed a better result with co-trimoxazole. The incidence of side-effects were higher in the group receiving tetracycline compared with those receiving co-trimoxazole.
摘要
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