Onoe M, Oku H, Kitayama H, Matsumoto T, Kaneda T
Department of Cardiovascular Surgery, Kinki University School of Medicine, Osaka, Japan.
Surg Today. 2001;31(7):586-90. doi: 10.1007/s005950170091.
To evaluate the effectiveness of modified ultrafiltration (MUF) on ventricular septal defect (VSD) repair in children, we retrospectively examined 10 patients who underwent VSD repair with MUF at the Kinki University School of Medicine hospital between June 1998, and December 1998 (MUF group). These patients were compared with 14 patients who underwent the same procedure without MUF (control group) between January 1997 and June 1998. Systolic blood pressure and hematocrit values increased significantly during MUF. By the time of postoperative transfer to the intensive care unit, PaO2 was higher in the MUF group than in the control group (503.3 +/- 112.2mmHg vs 376.3 +/- 149.2mmHg; P = 0.0491), whereas A-aDO2 was lower in the MUF group than in the control group (171.9 +/- 109.2mmHg vs 301.1 x 150.4mmHg; P = 0.0449). These findings demonstrate that MUF had a beneficial effect on pulmonary function in children who underwent surgery to repair a VSD.
为评估改良超滤（MUF）对儿童室间隔缺损（VSD）修补术的有效性，我们回顾性研究了1998年6月至1998年12月期间在近畿大学医学院医院接受VSD修补术并使用MUF的10例患者（MUF组）。将这些患者与1997年1月至1998年6月期间接受相同手术但未使用MUF的14例患者（对照组）进行比较。在MUF期间，收缩压和血细胞比容值显著升高。术后转至重症监护病房时，MUF组的动脉血氧分压（PaO2）高于对照组（503.3±112.2mmHg对376.3±149.2mmHg；P = 0.0491），而MUF组的肺泡-动脉氧分压差（A-aDO2）低于对照组（171.9±109.2mmHg对301.1±150.4mmHg；P = 0.0449）。这些发现表明，MUF对接受VSD修补手术的儿童的肺功能有有益影响。
