Oliak D, Yamini D, Udani V M, Lewis R J, Arnell T, Vargas H, Stamos M J
Department of Surgery, Harbor-UCLA Medical Center, 1000 West Carson Street, Torrance, CA 90509, USA.
Dis Colon Rectum. 2001 Jul;44(7):936-41. doi: 10.1007/BF02235479.
Our goal was to compare initial operative and nonoperative management for periappendiceal abscess complicating appendicitis.
This study is a retrospective review of 155 consecutive patients with appendicitis complicated by periappendiceal abscess treated between 1992 and 1998. Eighty-eight patients were treated initially nonoperatively, and 67 patients were treated operatively. All patients had localized abdominal tenderness and either computed tomography or intraoperative documentation of an abscess.
Our patient population consisted of 107 males and 48 females, with an average age of 33 (range, 16-75) years. Age, gender, comorbidity, white blood cell count, temperature, and heart rate did not differ significantly between groups. For the initial nonoperative management group, the failure rate was 5.8 percent and the appendicitis recurrence rate was 8 percent after a mean follow-up of 36 weeks. The response to treatment of the initial nonoperative group and the initial operative group was compared by length of stay (9 +/- 5 days vs. 9 +/- 3 days; P = not significant), days until white blood cell count normalized (3.8 +/- 4 days vs. 3.1 +/- 3 days; P = not significant), days until temperature normalized (3.2 +/- 3 days vs. 3.1 +/- 2 days; P = not significant), and days until a regular diet was tolerated (4.7 +/- 4 days vs. 4.6 +/- 3 days; P = not significant). Complication rate was significantly lower in the nonoperative group (17 vs. 36 percent; P = 0.008).
Initial nonoperative management of appendicitis complicated by periappendiceal abscess is safe and effective. Patients undergoing initial nonoperative management have a lower rate of complications, but they are at risk for recurrent appendicitis.
我们的目标是比较阑尾周围脓肿合并阑尾炎的初始手术治疗和非手术治疗。
本研究是对1992年至1998年间连续治疗的155例阑尾周围脓肿合并阑尾炎患者的回顾性分析。88例患者最初接受非手术治疗,67例患者接受手术治疗。所有患者均有局限性腹部压痛,且通过计算机断层扫描或术中记录证实存在脓肿。
我们的患者群体包括107名男性和48名女性,平均年龄为33岁(范围16 - 75岁)。两组在年龄、性别、合并症、白细胞计数、体温和心率方面无显著差异。对于初始非手术治疗组,平均随访36周后,失败率为5.8%,阑尾炎复发率为8%。通过住院时间(9±5天对9±3天;P = 无显著差异)、白细胞计数恢复正常所需天数(3.8±4天对3.1±3天;P = 无显著差异)、体温恢复正常所需天数(3.2±3天对3.1±2天;P = 无显著差异)以及恢复正常饮食所需天数(4.7±4天对4.6±3天;P = 无显著差异)比较了初始非手术治疗组和初始手术治疗组对治疗的反应。非手术组的并发症发生率显著较低(17%对36%;P = 0.008)。
阑尾周围脓肿合并阑尾炎的初始非手术治疗是安全有效的。接受初始非手术治疗的患者并发症发生率较低,但有阑尾炎复发的风险。