Patapoutian A
Department of Cell Biology, ICND, The Scripps Research Institute, 92037, La Jolla, CA, USA.
Neuron. 2001 Jul 19;31(1):4-6. doi: 10.1016/s0896-6273(01)00352-x.
Dorsal root ganglia (DRG) neurons include multiple types of sensory neurons with well-appreciated anatomical and physiological distinctions. In this issue of Neuron, Chen et al. adds to our molecular understanding of these differences by reporting that DRG11, a paired homeodomain transcription factor, is specifically required for the proper development of pain-sensing nociceptive neurons.
背根神经节（DRG）神经元包括多种类型的感觉神经元，它们在解剖学和生理学上有明显的区别。在本期《神经元》杂志中，陈等人报告称，配对同源结构域转录因子DRG11是痛觉感受性伤害性神经元正常发育所特别需要的，这增加了我们对这些差异的分子层面的理解。
