Zhang Y, Deng Y P, Guan X M
Department of Neurobiology, Tongji Medical University, Wuhan 430030.
Sheng Li Xue Bao. 1999 Aug;51(4):371-6.
The dorsal roots (DR) of L2-L3 segments on the left side in anesthetized rats (n = 28) were exposed and transected. After stimulating the peripheral endings of L2 DR with a train of square waves (0.8-1.2 mA, 100 Hz, 0.5 ms) for 2 s, the discharges at the distal end of transected L3 DR were recorded for 120 s. We found that the mean discharge frequency (MDF) of L3 DR was gradually increased with L2 DR stimulation. Time course analysis showed that the increase in MDF was linearly correlative to the number of stimuli, as well as to the levels of spontaneous discharge of L3 DR. The above results suggest that the transegmental information transmission between peripheral endings of primary sensory neurons may occur through a chemical non-synaptic way.
在麻醉大鼠（n = 28）身上暴露并切断左侧L2 - L3节段的背根（DR）。在用一串方波（0.8 - 1.2 mA，100 Hz，0.5 ms）刺激L2背根的外周端2秒后，记录切断的L3背根远端120秒的放电情况。我们发现，随着对L2背根的刺激，L3背根的平均放电频率（MDF）逐渐增加。时程分析表明，MDF的增加与刺激次数以及L3背根的自发放电水平呈线性相关。上述结果表明，初级感觉神经元外周端之间的节段间信息传递可能通过化学性非突触方式发生。
