[网状脱细胞真皮异种移植物（猪皮）与自体断层皮片联合应用于23例患者]
[The application of meshed acellular dermis xenograft (pigskin) with split thickness skin autograft in 23 patients].
作者信息
Feng X, Pan Y, Tan J
机构信息
Department of burns, Fushan first Hospital, Fushan 528000, PR China.
出版信息
Zhonghua Zheng Xing Wai Ke Za Zhi. 2000 Jan;16(1):40-2.
OBJECTIVE
An effective and inexpensive coverage, which can prevent scar formation and fill up scar tissue depression for full thickness skin burns in 23 patients was presented.
METHODS
A deepithelized and acellular basement membranes of dermis from freshly harvested pigskin was obtained as meshed acellular dermis xenograft. The patients were treated in one or two stages. Two stages, 7 day postoperative the meshed acellular xenograft, a split thickness skin autograft was applied. One stage, the meshed acellular xenograft and split thickness skin autograft were applied at same time.
RESULTS
The take rate of two staged treatment was (87.0 +/- 25.4)% and one stage was (60.3 +/- 3.4)%. All grafts showed in pink or near normal skin color and felt soft and smooth.
CONCLUSIONS
The combination of meshed acellular dermis xenograft and split thickness skin autograft demonstrated an ideal way for the coverage of full thickness skin burn, which is effective and inexpensive.
目的
介绍一种有效且经济的覆盖方法，该方法可防止23例全层皮肤烧伤患者形成瘢痕并填充瘢痕组织凹陷。
方法
从新鲜获取的猪皮中获得去上皮化且无细胞的真皮基底膜，制成网状无细胞真皮异种移植物。患者接受一阶段或两阶段治疗。两阶段治疗是在术后7天应用网状无细胞异种移植物，然后进行薄层自体皮移植。一阶段治疗是同时应用网状无细胞异种移植物和薄层自体皮移植。
结果
两阶段治疗的成活率为（87.0±25.4）%，一阶段治疗的成活率为（60.3±3.4）%。所有移植物均呈现粉红色或接近正常肤色，触感柔软光滑。
结论
网状无细胞真皮异种移植物与薄层自体皮移植相结合是全层皮肤烧伤覆盖的理想方法，有效且经济。
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