食物摄入对大鼠回肠切除术后结构和功能适应性发展的影响。
The influence of food intake on the development of structural and functional adaptation following ileal resection in the rat.
作者信息
Menge H, Gräfe M, Lorenz-Meyer H, Riecken E O
出版信息
Gut. 1975 Jun;16(6):468-72. doi: 10.1136/gut.16.6.468.
Abstract
The present study was undertaken to determine the influence of hyperphagia on the adaptive changes occurring in the rat jejunal mucosa as a result of intestinal resection. One group of resected rats was subjected to pair feeding with a sham-operated population, whilst another group was nourished ad libitum. The animals which ate ad libitum developed hypertrophy of the mucosa which was accompanied by increased glucose absorption in vivo without changes in enzyme levels. These alterations were much less pronounced in the pair-fed group of resected animals, a finding that indicates that the adaptive changes are at least partially influenced by increased luminal nutrition.
摘要
本研究旨在确定摄食过量对大鼠空肠黏膜因肠切除而发生的适应性变化的影响。一组切除肠段的大鼠与假手术组大鼠进行配对喂食，而另一组则随意进食。随意进食的动物出现了黏膜肥大，同时体内葡萄糖吸收增加，但酶水平没有变化。在配对喂食的切除肠段动物组中，这些变化则不太明显，这一发现表明适应性变化至少部分受到肠腔内营养增加的影响。
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Intestinal hypertrophy following partial resection of the small bowel in the rat.大鼠小肠部分切除术后的肠道肥大
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The nutritive effect of glucose on the structure and function of jejunal self-emptying blind loops in the rat.葡萄糖对大鼠空肠自排空盲袢结构和功能的营养作用。
Gut. 1975 Jun;16(6):462-7. doi: 10.1136/gut.16.6.462.
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