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胰腺和肠道对鸟类脂肪分解调节的作用。I. 回肠提取物中高效脂肪分解因子的存在。

The contribution of the pancreas and the intestine to the regulation of lipolysis in birds. I. Existence of highly potent lipolytic factors in ileum extracts.

作者信息

Krug E, Mialhe P

出版信息

Horm Metab Res. 1975 Jul;7(4):305-9. doi: 10.1055/s-0028-1093719.

Abstract

Duck intestinal extracts were separated into three main peaks of proteins by chromatography on P6 BioGel columns. The first, which crossreacted with glucagon antibodies, gut "GLI", did not stimulate lipolysis in isolated chicken adipocytes. Both second and third peaks, corresponding to smaller molecular-size peptides were even more lipolytic than pancreatic glucagon.

摘要

鸭肠提取物通过在P6生物凝胶柱上进行色谱分离,得到三个主要的蛋白质峰。第一个峰与胰高血糖素抗体发生交叉反应,即肠道“GLI”,它不会刺激分离的鸡脂肪细胞中的脂肪分解。第二个和第三个峰对应于较小分子量的肽,它们的脂肪分解作用甚至比胰高血糖素更强。

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