ε-氨基己酰氨基酸对蛋白水解酶活性的影响。
Effect of epsilon-aminocaproylaminoacids on the activity of proteolytic enzymes.
作者信息
Bruzgo I, Midura-Nowaczek K, Roszkowska-Jakimiec W, Jasielczuk J
机构信息
Institute of Chemistry, University of Białystok, Poland.
出版信息
Acta Pol Pharm. 2001 Mar-Apr;58(2):137-40.
PMID:11501792
Abstract
Effect of three epsilon-aminocaproylaminoacids with significant antifibrinolytic activity on chymotrypsin, trypsin, cathepsin B, cathepsin C and cathepsin D activities was examined. Slight inhibition of trypsin and chymotrypsin activity was observed only at high concentrations of these compounds. All tested dipeptides did not influence activities of cathepsin B, cathepsin C and cathepsin D.
摘要
研究了三种具有显著抗纤维蛋白溶解活性的ε-氨基己酰氨基酸对胰凝乳蛋白酶、胰蛋白酶、组织蛋白酶B、组织蛋白酶C和组织蛋白酶D活性的影响。仅在这些化合物的高浓度下观察到对胰蛋白酶和胰凝乳蛋白酶活性的轻微抑制。所有测试的二肽均不影响组织蛋白酶B、组织蛋白酶C和组织蛋白酶D的活性。
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