Bruzgo Irena, Midura-Nowaczek Krystyna, Bruzgo Magdalena, Kaczyńska Joanna, Roszkowska-Jakimiec Wiesława
Department of Organic Chemistry, Medical University of Białystok, Kilińskiego Str. 1, 15-089 Białystok, Poland.
Acta Pol Pharm. 2006 Mar-Apr;63(2):149-52.
Effect of three epsilon-aminocaproylamino acids with significant antifibrinolytic activity on polymerization of fibrin monomer, clot retraction, fibrin structure, prothrombin consumption and thrombin activity was examined. epsilon-Aminocaproyl-L-norleucine and epsilon-aminocaproyl-L-leucine were weak inhibitors of thrombin activity and epsilon-aminocaproyl-L-norleucine slightly inhibited polymerization of fibrin monomers.
