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Demonstration of a factor in the serum of homozygotes and heterozygotes for cystic fibrosis by a non-biological technique.

作者信息

Altland K, Schmidt S R, Kaiser G, Knoche W

出版信息

Humangenetik. 1975 Jul 23;28(3):207-16. doi: 10.1007/BF00278546.

DOI:10.1007/BF00278546
PMID:1150280
Abstract

A factor has been isolated from serum of homozygotes and obligate heterozgotes for cystic fibrosis using isoelectric focusing and disc electrophoresis as analytical methods. The factor is focused within an IgG-fraction with an isoelectric point of pH 8 to 9 but differs from IgG in its lower molecular weight. It is thus similar to, if not identical with, the ciliary dyskinesia factor.

摘要

相似文献

1
Demonstration of a factor in the serum of homozygotes and heterozygotes for cystic fibrosis by a non-biological technique.
Humangenetik. 1975 Jul 23;28(3):207-16. doi: 10.1007/BF00278546.
2
Studies on cystic fibrosis using isoelectric focusing. IV. Distinction between ciliary dyskinesia activity in cystic fibrosis and asthmatic sera and association of cystic fibrosis protein with the activity in cystic fibrosis serum.利用等电聚焦技术对囊性纤维化的研究。IV. 囊性纤维化血清与哮喘血清中纤毛运动障碍活性的差异以及囊性纤维化蛋白与囊性纤维化血清中该活性的关联
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3
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2
Detection of cystic fibrosis homozygotes and heterozygotes by serum isoelectrofocusing.
Hum Genet. 1981;56(3):387-9. doi: 10.1007/BF00274698.
3
Polymorphism of the haptoglobin peptides by isoelectric focusing electrophoresis and isoelectric point determinations.通过等电聚焦电泳和等电点测定法研究触珠蛋白肽的多态性。
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本文引用的文献

1
Disk electrophoresis of basic proteins and peptides on polyacrylamide gels.碱性蛋白质和肽在聚丙烯酰胺凝胶上的圆盘电泳。
Nature. 1962 Jul 21;195:281-3. doi: 10.1038/195281a0.
2
"Molecular sieve" chromatography on polyacrylamide gels, prepared according to a simplified method.根据简化方法制备的聚丙烯酰胺凝胶上的“分子筛”色谱法。
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Hum Genet. 1985;70(2):168-71. doi: 10.1007/BF00273076.
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Oyster ciliary inhibition by cystic fibrosis factor.囊性纤维化因子对牡蛎纤毛的抑制作用。
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5
Cystic fibrosis: characterization of the inhibitor to ciliary action in oyster gills.囊性纤维化：牡蛎鳃中纤毛运动抑制剂的特性
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6
Inhibition of the motility of gill cilia of Dreissensia by plasma of cystic fibrosis patients and their parents.囊性纤维化患者及其父母的血浆对斑马贻贝鳃纤毛运动的抑制作用。
J Med Genet. 1969 Sep;6(3):278-80. doi: 10.1136/jmg.6.3.278.
7
Fractionation of oyster cilia inhibitor from cystic fibrosis heterozygote serum.从囊性纤维化杂合子血清中分离牡蛎纤毛抑制剂。
Biochem Biophys Res Commun. 1972 Mar 10;46(5):1923-7. doi: 10.1016/0006-291x(72)90071-x.
8
Arginine esterase in cystic fibrosis of the pancreas.胰腺囊性纤维化中的精氨酸酯酶。
Pediatr Res. 1974 Jun;8(6):684-6. doi: 10.1203/00006450-197406000-00010.
9
Plasma arginine esterase activity in cystic fibrosis.
Am Rev Respir Dis. 1974 Mar;109(3):399-401. doi: 10.1164/arrd.1974.109.3.399.
10
Studies on ciliary dyskinesia factor in cystic fibrosis. IV. Its possible identification as anaphylatoxin (C3a)-IgG complex.囊性纤维化中纤毛运动障碍因子的研究。IV. 其可能被鉴定为过敏毒素（C3a）-IgG复合物。
Life Sci. 1974 Jan 16;14(2):253-66. doi: 10.1016/0024-3205(74)90055-1.