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血管紧张素转换酶抑制剂和血管紧张素II受体拮抗剂在高血压治疗中的益处。

Benefits of angiotensin converting enzyme inhibition and angiotensin II receptor antagonists in hypertension.

作者信息

Conlin P R

机构信息

Endocrinology-Hypertension Division, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.

出版信息

J Med Liban. 2000 Nov-Dec;48(6):382-6.

PMID:11503531
Abstract

It is through blood pressure lowering that reductions in cardiovascular morbidity and mortality are achieved. The treatment of hypertension patients should also focus on prevention and management of cardiovascular complications, not merely on achieving a target level of blood pressure. In making treatment decisions it is appropriate to assess patients for the presence or absence of risk factors and/or clinical cardiovascular disease. Clinicians should strive to use the least intrusive means possible to achieve goal blood pressure and the treatment regiment should be individualized for each patient. The review has illustrated specific clinical conditions where the use of an hypertensive agent that inhibits the renin-angiotensin system may offer added benefit to the patient while producing the needed anti-hypertensive effects.

摘要

通过降低血压可实现心血管发病率和死亡率的降低。高血压患者的治疗还应侧重于心血管并发症的预防和管理,而不仅仅是达到目标血压水平。在做出治疗决策时,评估患者是否存在危险因素和/或临床心血管疾病是恰当的。临床医生应努力采用尽可能少侵入性的方法来实现目标血压,并且治疗方案应针对每个患者进行个体化。该综述阐述了一些特定的临床情况,即使用抑制肾素 - 血管紧张素系统的抗高血压药物可能在产生所需的抗高血压作用的同时为患者带来额外益处。

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