Calvo Romero J M, Ramos Salado J L, García de la Llana F, Bureo Dacal J C, Bureo Dacal P, Pérez Miranda M
Servicio de Medicina Interna, Hospital Regional Universitario Infanta Cristina, Badajoz.
An Med Interna. 2001 Jun;18(6):309-11.
To identify potential differences in the clinical and laboratory characteristics between tuberculous spondylitis (TS) and brucellar spondylitis (BS).
Retrospective study of patients with TS and BS diagnosed in our hospital between january 1992 and december 1998.
TS was diagnosed in 17 patients and BS in 10 patients. In our series, a higher delay in the diagnosis (27.9 +/- 24.6 vs. 16 +/- 5.6 weeks, p = 0.02) was found in TS. There was a higher frequency, but without stadistic significance, of immunosuppression, one or several paravertebral or epidural abscesses, spinal cord compression, anemia and an elevated erythrocyte sedimentation rate in TS, and a higher frequency of fever/febricule and residual vertebral pain in BS. Lumbar location was the most frequent in both groups (58.8% in TS and 70% in BS).
It is possible that there were some differences in the clinical and laboratory characteristics between TS and BS which may be an aid in the differential diagnosis of both entities and orient the empirical treatment in these cases without a definitive microbiological diagnosis or while awaiting the diagnostic confirmation.
确定结核性脊柱炎（TS）和布鲁菌性脊柱炎（BS）在临床及实验室特征方面的潜在差异。
对1992年1月至1998年12月间在我院诊断为TS和BS的患者进行回顾性研究。
确诊TS患者17例，BS患者10例。在我们的研究系列中，TS患者诊断延迟时间更长（27.9±24.6周对16±5.6周，p = 0.02）。TS患者免疫抑制、一个或多个椎旁或硬膜外脓肿、脊髓受压、贫血及红细胞沉降率升高的发生率更高，但无统计学意义，而BS患者发热/微热及残留椎体疼痛的发生率更高。两组中腰椎受累最为常见（TS组为58.8%，BS组为70%）。
TS和BS在临床及实验室特征方面可能存在一些差异，这可能有助于两者的鉴别诊断，并在这些未明确微生物诊断或等待诊断确认的病例中指导经验性治疗。
