Handa V L, Danielsen B H, Gilbert W M
Department of Obstetrics and Gynecology, University of California Davis School of Medicine, Sacramento, California, USA.
Obstet Gynecol. 2001 Aug;98(2):225-30. doi: 10.1016/s0029-7844(01)01445-4.
To estimate the frequency of obstetric anal sphincter laceration and to identify characteristics associated with this complication, including modifiable risk factors.
A population-based, retrospective study of over 2 million vaginal deliveries at California hospitals was performed, using information from birth certificates and discharge summaries for 1992 through 1997. We excluded preterm births, stillbirths, breech deliveries, and multiple gestations. The main outcome measure was obstetric anal sphincter laceration (third and fourth degree).
The frequency of anal sphincter lacerations was 5.85% (95% confidence interval [CI] 5.82, 5.88), decreasing significantly from 6.35% (95% CI 6.27, 6.43) in 1992 to 5.43% (95% CI 5.35, 5.51) in 1997 (P <.01). Using logistic regression analysis, we identified primiparity as the dominant risk factor (odds ratio [OR] for women with prior vaginal birth 0.15; 95% CI 0.14, 0.15). Birth weight over 4000 g was also highly significant (OR 2.17; 95% CI 2.07, 2.27). Lacerations occurred more often among women of certain racial and ethnic groups: Indian women (OR 2.5; 95% CI 2.23, 2.79) and Filipina women (OR 1.63; 95% CI 1.50, 1.77) were at highest risk. Episiotomy decreased the likelihood of third-degree lacerations (OR 0.81; 95% CI 0.78, 0.85), but increased the risk of fourth-degree lacerations (OR 1.12; 95% CI 1.05, 1.19). Operative delivery increased the risk of sphincter laceration, with vacuum delivery (OR 2.30; 95% CI 2.21, 2.40) presenting a greater risk than forceps delivery (OR 1.45; 95% CI 1.37, 1.52).
Anal sphincter lacerations are strongly associated with primiparity, macrosomia, and operative vaginal delivery. Of the modifiable risk factors, operative vaginal delivery remains the dominant independent variable.
评估产科肛门括约肌裂伤的发生率,并确定与该并发症相关的特征,包括可改变的危险因素。
利用1992年至1997年出生证明和出院小结中的信息,对加利福尼亚州医院超过200万例阴道分娩进行了一项基于人群的回顾性研究。我们排除了早产、死产、臀位分娩和多胎妊娠。主要结局指标是产科肛门括约肌裂伤(三度和四度)。
肛门括约肌裂伤的发生率为5.85%(95%置信区间[CI]5.82,5.88),从1992年的6.35%(95%CI6.27,6.43)显著下降至1997年的5.43%(95%CI5.35,5.51)(P<.01)。通过逻辑回归分析,我们确定初产是主要危险因素(既往有阴道分娩史的女性的优势比[OR]为0.15;95%CI0.14,0.15)。出生体重超过4000g也具有高度显著性(OR2.17;95%CI2.07,2.27)。某些种族和族裔群体的女性裂伤发生率更高:印度女性(OR2.5;95%CI2.23,2.79)和菲律宾女性(OR1.63;95%CI1.50,1.77)风险最高。会阴切开术降低了三度裂伤的可能性(OR0.81;95%CI0.78,0.85),但增加了四度裂伤的风险(OR1.12;95%CI1.05,1.19)。手术分娩增加了括约肌裂伤的风险,但真空吸引分娩(OR2.30;95%CI2.21,2.40)的风险高于产钳分娩(OR1.45;95%CI1.37,1.52)。
肛门括约肌裂伤与初产、巨大儿和阴道手术分娩密切相关。在可改变的危险因素中,阴道手术分娩仍然是主要的独立变量。