存在还是不存在：B-Raf的问题？

To be or not to be: a question of B-Raf?

作者信息

Kolch W

机构信息

Institute for Biomedical and Life Sciences, University of Glasgow, Glasgow, UK.

出版信息

Trends Neurosci. 2001 Sep;24(9):498-500. doi: 10.1016/s0166-2236(00)01889-0.

DOI:10.1016/s0166-2236(00)01889-0

PMID:11506871

Abstract

A recent study has identified the B-Raf gene as essential for the survival of explanted sensory and motor neurons in culture in response to neurotrophic factors. This finding sheds new light on the control of neuronal development and poses new questions with regard to Raf-isozyme-specific functions.

摘要

最近的一项研究已确定，B-Raf基因对于体外培养的感觉神经元和运动神经元在神经营养因子作用下的存活至关重要。这一发现为神经元发育的控制提供了新的线索，并就Raf同工酶的特定功能提出了新的问题。