Leighton P C, Langley F A
J Clin Pathol. 1975 May;28(5):394-402. doi: 10.1136/jcp.28.5.394.
A long-term review of 108 women suffering from various forms of vulval dermatosis is described and a detailed analysis of those with chronic hypertrophic vulvitis, lichen sclerosus et atrophicus, and neurodermatitis is made. One case of neurodermatitis and two cases of lichen sclerosus progressed to carcinoma but no case of chronic hypertrophic vulvitis became malignant. It is possible that vulval dermatoses occur more commonly in the nulliparous than in the parous women and there is a slight preponderance of women who are blood group A. It is suggested that the term "leukoplakia" should be abandoned and that vulval lesions should be described in precise and meaningful histological terms.
本文描述了对108例患有各种形式外阴皮肤病的女性进行的长期回顾,并对慢性肥厚性外阴炎、硬化性苔藓萎缩性苔藓和神经性皮炎患者进行了详细分析。1例神经性皮炎和2例硬化性苔藓发展为癌症,但慢性肥厚性外阴炎无一例恶变。外阴皮肤病在未生育女性中可能比生育女性中更常见,并且A型血的女性略占多数。建议放弃“白斑病”这一术语,外阴病变应以精确且有意义的组织学术语来描述。