Punnonen R, Soidinmäki H, Kauppila O, Pystynen P
Ann Chir Gynaecol Suppl. 1985;197:23-5.
Lichen sclerosus et atrophicus was an associated lesion in 16 of 30 (53%) patients with invasive vulvar carcinoma. In one case invasive carcinoma developed in the background of lichen sclerosus et atrophicus. Additionally in one case lichen sclerosus was found at the margin of the carcinoma. Despite the low malignant potential, patients with vulvar lichen sclerosus et atrophicus need long-standing observation and recurrent histologic examinations.
萎缩性硬化性苔藓是30例浸润性外阴癌患者中16例（53%）的相关病变。1例浸润性癌在萎缩性硬化性苔藓背景下发生。另外1例在癌边缘发现有萎缩性硬化性苔藓。尽管恶性潜能低，但外阴萎缩性硬化性苔藓患者仍需要长期观察及反复组织学检查。
