Lolas F
Programa Regional de Bioética OPS/OMS, Providencia 1017-Piso 7, Santiago de Chile.
Rev Med Chil. 2001 Jun;129(6):680-4.
Most codes and declarations pertaining to the ethics of research involving human subjects have been formulated in response to specific events mostly of a painful or embarrassing nature. Several concepts appearing repeatedly in their texts are highlighted in this paper: principles of respect for persons, beneficence and justice, vulnerability and research propriety. Along with some comments on current revisions of many international guidelines and the role of bioethics committees, a plea is made to have a proactive rather than a reactive stance in ethical regulation of biomedical research.
大多数涉及人类受试者研究伦理的准则和声明都是针对大多具有痛苦或尴尬性质的特定事件而制定的。本文着重介绍了在这些文本中反复出现的几个概念:尊重人的原则、有益和公正、脆弱性和研究适当性。除了对许多国际准则当前修订情况以及生物伦理委员会的作用的一些评论外,本文呼吁在生物医学研究的伦理监管方面采取积极主动而非被动应对的立场。