Cortese A F, Cornell G N
J Am Geriatr Soc. 1975 Aug;23(8):337-42. doi: 10.1111/j.1532-5415.1975.tb00323.x.
Of 142 female patients over age 75 at The New York Hospital-Cornell Medical Center, 58 underwent radical mastectomy and 40 simple mastectomy for primary breast cancer. After five years, 19 per cent of the radical mastectomy group were cancer-free compared with 35 per cent of the simple mastectomy group. The gross five-year survival rates were 50 per cent and 47 per cent respectively. In the radical mastectomy group, when the axillary nodes did not show cancer at the time of operation, there have been no known recurrences and 70 per cent of the patients have survived at least five years. There was no surgical mortality. These findings support the view that until more controlled data are available, radical mastectomy is still the preferred therapy for primary breast cancer.
在纽约医院 - 康奈尔医学中心的142名75岁以上的女性患者中，58人因原发性乳腺癌接受了根治性乳房切除术，40人接受了单纯乳房切除术。五年后，根治性乳房切除术组中19%的患者无癌，而单纯乳房切除术组为35%。总体五年生存率分别为50%和47%。在根治性乳房切除术组中，若手术时腋窝淋巴结未发现癌细胞，则尚无已知复发情况，且70%的患者至少存活了五年。无手术死亡病例。这些发现支持了这样一种观点，即在获得更多对照数据之前，根治性乳房切除术仍是原发性乳腺癌的首选治疗方法。
