Ilves H, Hõrak R, Kivisaar M
Estonian Biocentre and Institute of Molecular and Cell Biology, Tartu University, 51010 Tartu, Estonia.
J Bacteriol. 2001 Sep;183(18):5445-8. doi: 10.1128/JB.183.18.5445-5448.2001.
Transpositional activity of mobile elements can be induced by different environmental stresses. Here, we present evidence that transposition of Tn4652 is elevated in stationary-phase Pseudomonas putida and suppressed in an isogenic sigma(S)-defective strain. We demonstrate that transcription from the Tn4652 transposase promoter is controlled by the stationary-phase-specific sigma factor sigma(S). To our knowledge, this is the first example of direct stationary-phase-specific regulation of a mobile element transposase. Data presented in this report support the idea that activation of transposition under stressful conditions could be an inducible process.
移动元件的转座活性可由不同的环境压力诱导。在此，我们提供证据表明，Tn4652在恶臭假单胞菌的稳定期转座增加，而在同基因的σ(S)缺陷菌株中受到抑制。我们证明，Tn4652转座酶启动子的转录受稳定期特异性σ因子σ(S)的控制。据我们所知，这是移动元件转座酶直接受到稳定期特异性调控的首个例子。本报告中的数据支持这样一种观点，即在压力条件下转座的激活可能是一个可诱导的过程。
