Avelar K E, Vieira J M, Antunes L C, Lobo L A, Antunes E N, Domingues R M, Ferreira M C
Bloco I, Centro de Ciências da Saúde, Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal de Rio de Janeiro, Cidade Universitária, Ilha do Fundão, CEP, 21941-590, Rio de Janeiro, Brazil.
Int J Antimicrob Agents. 2001 Aug;18(2):129-34. doi: 10.1016/s0924-8579(01)00354-5.
The results of this study show that there is a high frequency of resistant species in the Bacteroides fragilis group in the intestinal tract of children and adults in Brazil. B. fragilis was not studied. Of the 73 strains examined, B. distasonis was the most resistant species to penicillin, cefoxitin, cefotaxime and clindamycin. High rates of multiresistance were found, most commonly to penicillin and clindamycin (18 of 36 strains). High levels of beta-lactamase production were detected in isolates showing high resistance to penicillin and multiresistance to the cephamycins, suggesting a widespread dissemination of such resistance.
这项研究结果表明，在巴西儿童和成人肠道内的脆弱拟杆菌群中，耐药菌的出现频率很高。未对脆弱拟杆菌进行研究。在所检测的73株菌株中，解脲拟杆菌对青霉素、头孢西丁、头孢噻肟和克林霉素的耐药性最强。发现多重耐药率很高，最常见的是对青霉素和克林霉素耐药（36株菌株中有18株）。在对青霉素高度耐药且对头孢霉素多重耐药的分离株中检测到高水平的β-内酰胺酶产生，这表明这种耐药性广泛传播。
