细胞极性：两个T的故事。

Cell polarity: a tale of two Ts.

作者信息

Verde F

机构信息

Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, P.O. Box 016129, Miami, FL 33101-6129, USA.

出版信息

Curr Biol. 2001 Aug 7;11(15):R600-2. doi: 10.1016/s0960-9822(01)00362-1.

DOI:10.1016/s0960-9822(01)00362-1

PMID:11516965

Abstract

The microtubule cytoskeleton plays an important role in cell polarity. Central to this process in fission yeast is tea1p, a marker of polarized cell growth that is delivered to the cell surface in a microtubule-dependent fashion. Recent studies suggest that the actin-binding protein bud6p may be a tea1p effector.

摘要

微管细胞骨架在细胞极性中起重要作用。在裂殖酵母中，这一过程的核心是tea1p，它是极化细胞生长的标志物，以微管依赖的方式被递送到细胞表面。最近的研究表明，肌动蛋白结合蛋白bud6p可能是tea1p的效应物。