Shakhovskaia A K, Gmoshinskiĭ I V, Vasil'ev A V, Loranskaia T I, Ovchinnikova I V, Orlova L A, Mazo V K
Vopr Pitan. 2001;70(3):22-4.
Selenium level was determined in sera of 27 patients including 15 patients with chronic gastrointestinal diseases and 12 patients with intestinal malabsorption after some kinds of stomach or small intestine resection. Deficiency of this trace element was found in 5 patients and suboptimal concentration in 4 patients in the first group and in 3 and 5 patients of second group respectively. Supplementation of patients with 45 mg of selenium organic form based on autolysis extract of selenious baker's yeast resulted in increase of selenium level in 23 (85%) patients including all of them with selenium deficiency or suboptimal level. It was concluded about high bioavailability of selenium in supplement studied. Perturbed intestinal absorption after surgical resection of stomach or small intestine may be considered as an indication for prophylactic taking of organic selenium form preparation.
对27例患者的血清进行了硒水平测定，其中包括15例患有慢性胃肠疾病的患者以及12例在接受某种胃或小肠切除术后出现肠道吸收不良的患者。第一组中5例患者存在这种微量元素缺乏，4例患者浓度低于最佳水平；第二组中分别有3例和5例患者出现上述情况。基于亚硒酸面包酵母自溶提取物，对患者补充45毫克有机形式的硒，结果23例（85%）患者的硒水平升高，其中包括所有硒缺乏或低于最佳水平的患者。由此得出所研究的补充剂中硒具有高生物利用度的结论。胃或小肠手术切除后肠道吸收紊乱可被视为预防性服用有机硒制剂的指征。
