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[酒精对胃分泌作用的机制]

[Mechanism of alcohol action on gastric secretion].

作者信息

Vasilevskaia L S, Skurikhin I M, Guliev R R

出版信息

Vopr Pitan. 2001;70(3):9-11.

Abstract

In chronic experiment on dogs (3 dogs with Pavlov's miniature stomach, 3 dogs with Heidenhain's miniature stomach) the mechanism of action of alcohol (8%-150 ml) on gastric secretion was clarified. For this purpose the new inhibitor of gastric secretion--glycopeptide was utilized, which action was preset in laboratory of G.K. Shlygin. Was shown, that in effect of alcohol on gastric secretion take place the complicated mechanism including as a nervous regulation (vagus nerves), and humoral: participation of gastrin and histamine in secretory effect of a stomach, and also immediate effect of ethanol on acid glands.

摘要

在对狗进行的慢性实验中(3只带有巴甫洛夫小型胃的狗,3只带有海登海因小型胃的狗),阐明了酒精(8% - 150毫升)对胃液分泌的作用机制。为此,使用了新的胃液分泌抑制剂——糖肽,其作用由G.K. 什利金实验室预先设定。结果表明,酒精对胃液分泌的影响涉及复杂的机制,包括神经调节(迷走神经)和体液调节:胃泌素和组胺参与胃的分泌作用,以及乙醇对胃腺的直接作用。

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