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[体外血液净化对危重症患者脂质过氧化的影响]

[Effects of extracorporeal hemo-correction on lipid peroxidation in patients in critical states].

作者信息

Chalenko V V, Zhilkina S V, Pastukhova N K, Kutushev F Kh, Romanchishen A F

出版信息

Vestn Khir Im I I Grek. 2001;160(3):55-9.

Abstract

The article presents an analysis of immediate influence of extracorporeal hemocorrection upon the indices of lipid peroxidation in resuscitation patients of a surgical profile. It was found that hemosorption, ultrafiltration and their combination exert a moderate detoxicating effect on lipid peroxidation products. The detoxicating effect of plasmapheresis is negligible. Hemosorption and ultrafiltration fail to influence the mechanisms of antioxidant defense, plasmapheresis eliminates the antioxidant enzymes from blood plasma, and the methods of quantum therapy stimulate the activity of superoxide dismutase.

摘要

本文对体外血液净化对外科复苏患者脂质过氧化指标的即时影响进行了分析。结果发现,血液吸附、超滤及其联合应用对脂质过氧化产物具有中等程度的解毒作用。血浆置换的解毒作用可忽略不计。血液吸附和超滤不会影响抗氧化防御机制,血浆置换会从血浆中清除抗氧化酶,而量子疗法可刺激超氧化物歧化酶的活性。

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