Hall J A, Nelson M A, Meyer J W, Williamson T, Wagner S
Ingenix Pharmaceutical Services, Eden Prairie, Minnesota, USA.
Manag Care Interface. 2001 Aug;14(8):69-75.
The objectives of this study were to determine age- and gender-specific drug treatment prevalence rates for overactive bladder (OAB), and to compare resource use and costs among MCO members receiving drug treatment for OAB. Administrative claims data from seven affiliated health plans were analyzed for 8,661 members with a diagnosis or treatment indicative of OAB during 1998. Resource use and associated costs were analyzed over a four-month follow-up. In 1998, the prevalence of OAB among plan members was 1.1%. Of the patients with OAB, 71% did not receive pharmacotherapy. After multivariate analysis, treatment with tolterodine, oxybutynin, or other OAB treatment did not significantly affect the percent change in total per patient per month (PPPM) costs compared with the group not receiving a pharmacologic agent. Although the adjusted percent change in PPPM pharmacy costs was significantly higher within the tolterodine group, medical and total PPPM costs were not.
本研究的目的是确定膀胱过度活动症(OAB)的年龄和性别特异性药物治疗患病率,并比较接受OAB药物治疗的管理式医疗组织(MCO)成员之间的资源使用情况和成本。分析了来自七个附属健康计划的行政索赔数据,这些数据涉及1998年期间8661名有OAB诊断或治疗指征的成员。在四个月的随访期间分析了资源使用情况和相关成本。1998年,计划成员中OAB的患病率为1.1%。在患有OAB的患者中,71%未接受药物治疗。多变量分析后,与未接受药物治疗的组相比,使用托特罗定、奥昔布宁或其他OAB治疗对每位患者每月总成本(PPPM)的百分比变化没有显著影响。虽然托特罗定组内PPPM药房成本的调整后百分比变化显著更高,但医疗和总PPPM成本并非如此。