Miyoshi K
Hyogo Institute for Aging Brain & Cognitive Disorders.
Nihon Rinsho. 2001 Aug;59(8):1570-3.
Depression is a most common psychiatric complication of Parkinson's patients. Approximately 30% of Parkinson's patients show depressive mood changes. Loss of interest, feelings of hopelessness, marked loss of energy and psychomotor retardation are common depressive symptoms with parkinsonism. Suicidal ideations and delusions are less frequent in Parkinson's patients with depression in compared to endogenous depression. Somatic symptoms, like fatigue, constipation, headache, insomnia, loss of appetite, dizzinees and sweating are usually seen in Parkinson's patient with depression. Serotonin reuptake inhibitors and selegiline are recommended for the treatment of depression in parkinsonian patients.
抑郁症是帕金森病患者最常见的精神并发症。约30%的帕金森病患者出现情绪抑郁变化。兴趣丧失、绝望感、明显的精力丧失和精神运动迟缓是帕金森病常见的抑郁症状。与内源性抑郁症相比,帕金森病伴发抑郁症患者的自杀观念和妄想较少见。帕金森病伴发抑郁症患者通常会出现躯体症状,如疲劳、便秘、头痛、失眠、食欲不振、头晕和出汗。5-羟色胺再摄取抑制剂和司来吉兰被推荐用于治疗帕金森病患者的抑郁症。