Ignat F, Godeanu L, Davidescu L, Voiculescu M
Clinica de Oftalmologie Craiova.
Oftalmologia. 2001;51(1):77-9.
The aim of the study is to research the immunoglobulins' concentration into the tears liquid and into the blood serum at the patients with acute affections of the anterior ocular pole. The study was accomplished on two groups of patients: one group with herpetic Keratitis, the other with anterior uveitis, the second having a different etiology--that the viral one. Another group of patients with senile cataract was used like witness-group. The immunoglobulins concentration were detected into the serum and into the tears by the Mancini method of the radial immunodiffusion. The results indicate a general immunodefficiency signed by the decrease of IgG and IgM into the serum on the one hand, and the increase of local defense mechanisms reflected on the growing of IgA and IgG level into the tears, on the other hand.
本研究的目的是研究眼前极急性病变患者泪液和血清中免疫球蛋白的浓度。该研究在两组患者中完成:一组为疱疹性角膜炎患者,另一组为前葡萄膜炎患者,后者病因不同——非病毒病因。另一组老年性白内障患者用作对照组。采用放射免疫扩散的曼奇尼方法检测血清和泪液中的免疫球蛋白浓度。结果表明,一方面血清中IgG和IgM减少表明存在全身免疫缺陷,另一方面泪液中IgA和IgG水平升高反映局部防御机制增强。