Okuyama S, Sato T, Takahashi K, Ito Y, Matsuzawa T
J Reticuloendothel Soc. 1975 Jun;17(6):353-60.
The radioassay technique with the 113mIndium-iron chondroitin sulfate colloid, developed in our laboratory, revealed that an isolated marrow reticuloendothelial activation takes place after bleeding 15 to 30 ml of blood per kg body weight from a rabbit. It parallels the erythropoietic response very well. The present stimulation method might deserve testing for studies where marrow reticuloendothelial function is important such as in cancer-bearing patients, the effects of anticancer chemotherapy and gross antigenization.
