Chang C, Floss H G, Peck G E
J Med Chem. 1975 May;18(5):505-9. doi: 10.1021/jm00239a014.
The natural abundance 13C magnetic resonance spectra of a series of sulfonamide drugs(sulfanilamide, sulfaguanidine,sulfathiazole, sulfasuxidine, sulfadiazine, sulfamerazine, sulfamethiazine, and sulfapyridine) have been determined at 25.15 MHz employing the pulse Fourier transform technique. The chemical shefts have been assigned with the aid of off-resonance and selective proton decoupling techniques, as well as by long-range carbon-13 proton coupling patterns.
采用脉冲傅里叶变换技术，在25.15兆赫的频率下测定了一系列磺胺类药物（磺胺、磺胺胍、磺胺噻唑、琥珀磺胺噻唑、磺胺嘧啶、磺胺甲基嘧啶、磺胺二甲嘧啶和磺胺吡啶）的天然丰度13C磁共振谱。借助于非共振和选择性质子去耦技术以及远程碳-13质子耦合模式对化学位移进行了归属。
