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严重受伤事故受害者一年随访时精神疾病发病率的预测。

Prediction of psychiatric morbidity in severely injured accident victims at one-year follow-up.

作者信息

Schnyder U, Moergeli H, Trentz O, Klaghofer R, Buddeberg C

机构信息

Psychiatric Department, University Hospital, Zurich, Switzerland.

出版信息

Am J Respir Crit Care Med. 2001 Aug 15;164(4):653-6. doi: 10.1164/ajrccm.164.4.2008087.

Abstract

The objective of this study was to assess the prevalence of posttraumatic stress disorder (PTSD) and symptoms of depression and anxiety in severely injured accident victims 1 yr posttrauma and to predict psychiatric morbidity by means of variables assessed shortly after the accident. The sample consisted of 106 consecutive patients with accidental injuries (mean Injury Severity Score = 21.9, mean Glasgow Coma Scale score = 14.4) admitted to the intensive care unit of a University Hospital. Patients with severe head injuries, suicide attempters, and victims of physical assault were excluded. At 1-yr follow-up, two patients (1.9%) had PTSD, and 13 (12.3%) had subsyndromal PTSD. Eighteen patients (17%) had clinically relevant symptoms of anxiety, and nine (8.5%) were depressed. Overall, 27 patients (25.5%) showed some form of psychiatric morbidity (full or subsyndromal PTSD and/or anxiety and/or depression). Logistic regression analysis, using 1-yr psychiatric morbidity status as the dependent variable, allowed correct classification of 83.8% of patients 12 mo postaccident (specificity 91.8%, sensitivity 61.5%). Biographical risk factors and a sense of death threat contributed significantly to the predictive model. We conclude that a substantial proportion of severely injured accident victims develop some form of psychiatric morbidity that can be predicted to some degree by mainly psychosocial variables.

摘要

本研究的目的是评估重伤事故受害者创伤后1年创伤后应激障碍(PTSD)、抑郁和焦虑症状的患病率,并通过事故后不久评估的变量预测精神疾病的发病情况。样本包括连续入住某大学医院重症监护病房的106例意外伤害患者(平均损伤严重程度评分=21.9,平均格拉斯哥昏迷量表评分=14.4)。排除重度颅脑损伤患者、自杀未遂者和身体攻击受害者。在1年随访时,2例患者(1.9%)患有PTSD,13例(12.3%)患有亚综合征PTSD。18例患者(17%)有临床相关焦虑症状,9例(8.5%)有抑郁症状。总体而言,27例患者(25.5%)表现出某种形式的精神疾病(完全或亚综合征PTSD和/或焦虑和/或抑郁)。以1年精神疾病发病状况作为因变量进行逻辑回归分析,对事故后12个月83.8%的患者进行了正确分类(特异性91.8%,敏感性61.5%)。传记式风险因素和死亡威胁感对预测模型有显著贡献。我们得出结论,相当一部分重伤事故受害者会出现某种形式的精神疾病,主要通过社会心理变量在一定程度上可以预测。

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