Yumura Y, Hara Y, Ida T
Department of Urology, National Atami Hospital.
Hinyokika Kiyo. 2001 Jul;47(7):505-8.
A 64-year-old man presented to our department with urinary retention. Rectal examination revealed a small and soft prostate. PSA was within the normal limits. Computed tomography showed a low-density area around the prostatic urethra and urethrography revealed an irregular prostatic urethra compressed by the prostate. We performed transurethral resection of prostate (TUR-P). On resectoscopy, jelly-like round substances were seen in the bladder. Prostatic urethra and bladder neck were covered with a jelly-like substance. Pathological diagnosis was mucinous adenocarcinoma of the prostate with bladder neck involvement. One month later after TUR-P, we performed radical cystoprostatectomy. Histological findings showed the cancer, of which 70-80% was composed of extracellular mucin lakes containing floating clumps of tumor cells. Mucin lake was stained with alcian blue and PAS. Immunohistochemical study revealed the tumor cells positive for carcinoembryonic antigen (CEA) and negative for prostatic specific antigen (PSA).
一名64岁男性因尿潴留前来我院就诊。直肠指检发现前列腺小且质地柔软。前列腺特异性抗原（PSA）在正常范围内。计算机断层扫描显示前列腺尿道周围有低密度区域，尿道造影显示前列腺尿道受压且不规则。我们进行了经尿道前列腺切除术（TUR-P）。在再次膀胱镜检查时，膀胱内可见果冻样圆形物质。前列腺尿道和膀胱颈被果冻样物质覆盖。病理诊断为前列腺黏液腺癌累及膀胱颈。TUR-P术后1个月，我们进行了根治性膀胱前列腺切除术。组织学检查发现肿瘤中70 - 80%由含有漂浮肿瘤细胞团块的细胞外黏液湖组成。黏液湖经阿尔辛蓝和过碘酸希夫染色。免疫组织化学研究显示肿瘤细胞癌胚抗原（CEA）阳性，前列腺特异性抗原（PSA）阴性。
