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[迁延性风湿热中与链球菌膜交叉反应的抗心脏抗体]

[Anticardiac antibodies, cross reacting with the membranes of streptococcus, in protracted rheumatic fever].

作者信息

Hasonova V A, Tarasevich N N, Bronzov I A, Nanaeva G K

出版信息

Kardiologiia. 1975 May;15(5):23-8.

PMID:1152330
Abstract

The anti-cardiac antibodies cross-reacting with the Streptococcal membranes were studied by the method of Zabriskie and co-authors in 162 patients with rheumatism in its active phase and in 181 control individuals. The anti-cardiac antibodies were found in over half of the rheumatic patients and far less frequently in the controls. At the same time in the majority of cases only those anti-cardiac antibodies that were found in the rheumatics possessed distinct cross-activity towards the A-streptococcal membranes. Most consistently were they found in those with a protracted course of the disease.

摘要

采用扎布里斯基及其合著者的方法,对162例处于活动期的风湿热患者和181名对照个体进行了与链球菌膜交叉反应的抗心肌抗体研究。超过半数的风湿热患者发现有抗心肌抗体,而对照组中出现的频率要低得多。同时,在大多数情况下,只有在风湿热患者中发现的那些抗心肌抗体对A组链球菌膜具有明显的交叉活性。在病程迁延的患者中发现这些抗体的情况最为一致。

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