Sycheva I M, Kramer A A
Kardiologiia. 1975 May;15(5):99-105.
The amount of metabolizing potassium in the body was determined by means of K-42 dilution in 20 normal individuals and in 108 patients with different degrees of cardiac failure and various severity of the oedema syndrome. The amount of metabolizing potassium was found to decrease gradually along with the increase of cardiac insufficiency. Both the absolute amount of the metabolically active fraction of potassium was decreasing, and the content of this cation per 1 kg of body weight. The decrease of the amount of metabolizing potassium in cases of severe circulatory insufficiency did not depend on the severity of the oedema syndrome. With the improvement of the state of the patient and the decrease of congestive manifestations the level of metabolizing potassium tended to rise. Nevertheless, some patients demonstrated a reduction of the metabolically active fraction of potassium. And, vice versa, along with a deterioration of the patient's state and an increase of cardiac insufficiency and elevation of potassium content in the body was sometimes noted.
通过K - 42稀释法测定了20名正常个体以及108名不同程度心力衰竭和不同严重程度水肿综合征患者体内参与代谢的钾含量。结果发现,随着心脏功能不全的加重,参与代谢的钾含量逐渐降低。不仅钾的代谢活性部分的绝对量在减少,而且每1千克体重中该阳离子的含量也在减少。严重循环功能不全患者体内参与代谢的钾含量降低与水肿综合征的严重程度无关。随着患者病情的改善和充血症状的减轻,参与代谢的钾水平趋于上升。然而,一些患者的钾代谢活性部分仍有所降低。反之,随着患者病情恶化、心脏功能不全加重,体内钾含量有时也会升高。