Gijtenbeek J M, Rosenblum M K, DeAngelis L M
Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Neurology. 2001 Aug 28;57(4):716-8. doi: 10.1212/wnl.57.4.716.
Most primary CNS lymphomas (PCNSL) are B-cell neoplasms; T-cell lymphomas are quite rare. The authors report two young patients with T-cell PCNSL who had a complete response to chemo- and radiotherapy but developed recurrent disease and died 11 and 13 months from diagnosis. The prognosis of T-cell PCNSL may be worse than that of comparable B-cell tumors.
大多数原发性中枢神经系统淋巴瘤(PCNSL)是B细胞肿瘤;T细胞淋巴瘤相当罕见。作者报告了两名患有T细胞PCNSL的年轻患者,他们对化疗和放疗有完全反应,但出现了复发性疾病,并在诊断后11个月和13个月死亡。T细胞PCNSL的预后可能比类似的B细胞肿瘤更差。