Shojania K G, Bero L A
Department of Medicine, University of California, San Francisco, San Francisco, Calif., USA.
Eff Clin Pract. 2001 Jul-Aug;4(4):157-62.
Systematic reviews of the literature are an important resource for clinicians. Unfortunately, the few published strategies for identifying these articles involve MEDLINE interfaces not widely available outside of academic medicine. In addition, the performance of these strategies is unknown.
To develop and evaluate a search strategy for identifying systematic reviews by using a publicly available MEDLINE interface (PubMed).
Diagnostic test assessment. DEFINITION OF SENSITIVITY: The proportion of recognized systematic reviews (indexed in the Cochrane Library's Database of Abstracts of Reviews of Effectiveness [DARE] or in ACP Journal Club) that are identified by the search strategy. DEFINITION OF POSITIVE PREDICTIVE VALUE: The proportion of articles identified in one of three sample searches (screening for colorectal cancer, thrombolytic therapy for venous thromboembolism, and treatment of dementia) that meet a minimum definition of systematic review.
Our PubMed search strategy identified 93 of 100 DARE-indexed systematic reviews, a sensitivity of 93% (95% CI, 86% to 97%). For the sample of systematic reviews drawn from ACP Journal Club (n = 103), the PubMed strategy achieved a sensitivity of 97% (CI, 91% to 99%). When the three sample search strings were used, approximately 50% of retrieved articles met our minimum definition of systematic review. In contrast, the similar precision of a PubMed search restricted to review-type articles (as indexed by MEDLINE) was less than 10%.
This search strategy identified most systematic reviews without over-whelming users with numerous false-positive results. A "single-click" filter based on this strategy is now available as part of the Clinical Queries feature of PubMed.
文献系统评价是临床医生的重要资源。不幸的是，目前已发表的用于识别这些文章的少数策略涉及医学学术领域之外未广泛使用的MEDLINE界面。此外，这些策略的性能尚不清楚。
开发并评估一种使用公开可用的MEDLINE界面（PubMed）识别系统评价的检索策略。
诊断性试验评估。敏感性定义：检索策略识别出的公认系统评价（在Cochrane图书馆的疗效评价文摘数据库[DARE]或《美国内科医师学会杂志俱乐部》中索引）的比例。阳性预测值定义：在三项样本检索（筛查结直肠癌、静脉血栓栓塞的溶栓治疗和痴呆症治疗）之一中识别出的符合系统评价最低定义的文章比例。
我们的PubMed检索策略在100篇DARE索引的系统评价中识别出93篇，敏感性为93%（95%CI，86%至97%）。对于从《美国内科医师学会杂志俱乐部》抽取的系统评价样本（n = 103），PubMed策略的敏感性为97%（CI，91%至99%）。当使用这三个样本检索词时，约50%的检索文章符合我们对系统评价的最低定义。相比之下，将PubMed检索限制在综述类文章（如MEDLINE索引）时的类似精确率不到10%。
该检索策略识别出了大多数系统评价，且不会因大量假阳性结果给用户带来负担。基于此策略的“一键式”过滤器现已作为PubMed临床查询功能的一部分提供。
