Grellet J, Curet P, Laemmel M G, Cazala P, Dighiero G, Binet J L
AJR Am J Roentgenol. 1979 Nov;133(5):797-803. doi: 10.2214/ajr.133.5.797.
In a retrospective study of lymphograms in 55 patients with chronic lymphatic leukemia observed 42-170 months, four lymphographic groups were established according to lymph node size and morphology. In group 1, the lymph nodes were only slightly enlarged and pathologic in appearance. In group 2, the nodes were moderately enlarged and appeared reticular. In groups 3 and 4 the nodes were greatly enlarged and appeared foamy, striated, or "ghostlike" (similar to those seen in lymphoma). The correlation between the lymphographic groups and a new clinical classification (stages O-IV), which has been demonstrated to have prognostic values, was statistically significant: clinical stage O and lymphographic group 1; clinical stages III and IV and lymphographic groups 2, 3, or 4. Clinical stages 1 and II were dispersed throughout the different lymphographic groups. Although the specific prognostic value of the results of lymphography is not apparent in clinical stages O-II, it does seem to be established in stages III and IV. In these stages, the number of deaths was significantly greater in patients in lymphographic groups 3 and 4 when compared with those in lymphographic group 2.
在一项对55例慢性淋巴细胞白血病患者进行的回顾性研究中，观察期为42 - 170个月，根据淋巴结大小和形态建立了四个淋巴造影组。在第1组中，淋巴结仅轻度肿大且外观呈病理性。在第2组中，淋巴结中度肿大且呈网状外观。在第3组和第4组中，淋巴结显著肿大且呈泡沫状、条纹状或“幽灵样”（类似于淋巴瘤中所见）。淋巴造影组与已被证明具有预后价值的新临床分类（O - IV期）之间的相关性具有统计学意义：临床O期与淋巴造影第1组；临床III期和IV期与淋巴造影第2、3或4组。临床I期和II期分布于不同的淋巴造影组中。尽管淋巴造影结果在临床O - II期的具体预后价值尚不明显，但在III期和IV期似乎已得到证实。在这些阶段，与淋巴造影第2组的患者相比，淋巴造影第3组和第4组的患者死亡人数显著更多。
