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自然应变和应变率能否量化局部心肌变形?一项针对健康受试者的研究。

Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects.

作者信息

Kowalski M, Kukulski T, Jamal F, D'hooge J, Weidemann F, Rademakers F, Bijnens B, Hatle L, Sutherland G R

机构信息

University Hospital Gasthuisberg, Department of Cardiology, Leuven, Belgium.

出版信息

Ultrasound Med Biol. 2001 Aug;27(8):1087-97. doi: 10.1016/s0301-5629(01)00388-x.

DOI:10.1016/s0301-5629(01)00388-x
PMID:11527595
Abstract

Strain rate (SR) and strain (epsilon) have been proposed as new ultrasound (US) indices for quantifying regional wall deformation, and can be measured from color Doppler myocardial data by determining the local spatial velocity gradient. The aim of this study was to define normal regional SR/epsilon values for both radial and longitudinal myocardial deformation. SR/epsilon profiles were obtained from 40 healthy volunteers. For radial deformation, posterior left ventricular (LV) wall SR/epsilon were calculated. For longitudinal, they were determined for basal, mid- and apical segments of the 1. septum; 2. lateral, 3. posterior and 4. anterior LV walls and for the 5. right ventricular (RV) lateral wall. SR/epsilon values describing radial deformation were higher than the corresponding SR/epsilon values obtained for longitudinal deformation. Longitudinal SR/epsilon were homogeneous throughout the septum and all LV walls. This was in contrast to the normal base-apex velocity gradient. The RV segmental SR/epsilon values were higher than those obtained from the corresponding LV wall and inhomogeneous (higher in the apical segments). SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation.

摘要

应变率(SR)和应变(ε)已被提议作为量化局部室壁变形的新超声(US)指标,并且可以通过确定局部空间速度梯度从彩色多普勒心肌数据中测量得到。本研究的目的是确定径向和纵向心肌变形的正常局部SR/ε值。从40名健康志愿者获取了SR/ε曲线。对于径向变形,计算左心室(LV)后壁的SR/ε。对于纵向变形,确定以下部位的SR/ε:1. 室间隔的基底段、中间段和心尖段;2. 左心室侧壁;3. 左心室后壁;4. 左心室前壁;以及5. 右心室(RV)侧壁。描述径向变形的SR/ε值高于纵向变形所获得的相应SR/ε值。纵向SR/ε在整个室间隔和所有左心室壁中是均匀的。这与正常的心底 - 心尖速度梯度相反。右心室节段性SR/ε值高于从相应左心室壁获得的值,并且是不均匀的(在心尖段更高)。SR/ε成像似乎是一种用于量化局部心肌变形的可靠技术。

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