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挥发油治疗打鼾者:一项随机、双盲、安慰剂对照试验。

Treatment of snorers with a volatile oil: a randomized, double-blind placebo-controlled trial.

作者信息

Ulfberg J, Nyström B

机构信息

Sleep Disorders Center, Avesta Hospital, Avesta, Sweden.

出版信息

ORL J Otorhinolaryngol Relat Spec. 2001 Sep-Oct;63(5):298-301. doi: 10.1159/000055762.

DOI:10.1159/000055762
PMID:11528274
Abstract

Snoring is a significant problem both for the patient and for the bed partner. Seventy-two male and female heavy snorers and their bed partners participated in a double-blinded, placebo-controlled study on the effects of a volatile oil administered by gargling. The patients were diagnosed as heavy snorers after they underwent overnight polysomnography showing that their apnea indexes were below 5, thus sleep apnea patients were not included in the study. The participants and their partners filled out evaluations concerning snoring intensity, mouth dryness, nasal stuffiness and the Epworth Sleepiness Scale prior to and after using the volatile oil or placebo for 14 consecutive nights. There were no statistically significant decreases in snoring as graded by the bed partner or in mouth dryness, nasal stuffiness, or the Epworth Sleepiness Scale scores graded by the patients who were randomized to use the volatile oil. The results of this study indicate that this volatile oil is not an effective treatment in patients presenting with symptoms of snoring.

摘要

打鼾对患者及其同床伴侣来说都是一个严重的问题。72名男性和女性重度打鼾者及其同床伴侣参与了一项双盲、安慰剂对照研究,该研究旨在探讨含漱一种挥发油的效果。这些患者在接受过夜多导睡眠监测后被诊断为重度打鼾者,监测结果显示他们的呼吸暂停指数低于5,因此睡眠呼吸暂停患者未纳入该研究。参与者及其伴侣在连续14晚使用挥发油或安慰剂之前和之后填写了有关打鼾强度、口腔干燥、鼻塞和爱泼华嗜睡量表的评估表。随机使用挥发油的患者在同床伴侣评估的打鼾情况、以及患者自身评估的口腔干燥、鼻塞或爱泼华嗜睡量表评分方面,均未出现具有统计学意义的下降。本研究结果表明,这种挥发油对有打鼾症状的患者并非一种有效的治疗方法。

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引用本文的文献

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A systematic review of the pharmacological approaches against snoring: can we count on the chickens that have hatched?一项关于抗打鼾药物治疗方法的系统评价:我们能指望已孵化出的小鸡吗?
Sleep Breath. 2015 Sep;19(3):1035-42. doi: 10.1007/s11325-015-1123-0. Epub 2015 Feb 14.
2
Diagnosis and treatment of snoring in adults-S2k Guideline of the German Society of Otorhinolaryngology, Head and Neck Surgery.成人打鼾的诊断与治疗——德国耳鼻咽喉头颈外科学会S2k指南
Sleep Breath. 2015 Mar;19(1):135-48. doi: 10.1007/s11325-014-0979-8. Epub 2014 Apr 13.
3
[Sk2 guidelines"diagnosis and therapy of snoring in adults" : compiled by the sleep medicine working group of the German Society of Otorhinolaryngology, Head and Neck Surgery].
[《Sk2指南:成人打鼾的诊断与治疗》:由德国耳鼻咽喉头颈外科学会睡眠医学工作组编撰]
HNO. 2013 Nov;61(11):944-57. doi: 10.1007/s00106-013-2775-3.