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[动物实验中一种小孢子癣菌属物种盾片有明显荧光的研究]

[Study on a Trichophyton quinckeanum species with a distinctly marked fluorescence of the scutulum in animal experiments].

作者信息

Rodermund O E, Heymer T, De Vries G A

出版信息

Mycopathologia. 1975 Jul 30;56(1):31-4. doi: 10.1007/BF00493580.

Abstract

A vesicular skin lesion which existed since 1 week in the lower part of the leg of a 45-year-old woman appeared to be caused by fungus which was identified as Trichophyton quinckeanum (Zopf) MacLeod & Muende. The patient could not state to have had contact with animals. Peroral administration of griseofulvin and local application of 2% salicyl--5% sulfur--vaseline alternate with tonoftal cream healed the lesion completely. The fast growing fungus produced white, convoluted colonies with a brown, lat er wine-red reverse. Globose and club-shaped, one- and two-celled microconidia were formed especially 'en thrse'. The majority of the thin-walled macroconidia had rounded apices but a fusiform type of spore was also seen. Germination of the macroconidia was frequently observed. Experimental infection into the dorsal skin of white laboratory mouse produced a scutulum with a bright yellow later green fluorescence in Wood's light. The taxonomy of Trichophyton quinckeanum is briefly discussed.

摘要

一名45岁女性小腿下部出现水疱性皮肤病变已有1周,似乎是由真菌引起,该真菌被鉴定为昆克毛癣菌(Trichophyton quinckeanum,Zopf)MacLeod & Muende。患者称未与动物接触过。口服灰黄霉素并局部交替使用2%水杨酸-5%硫磺-凡士林和托萘酯乳膏,病变完全愈合。这种生长迅速的真菌产生白色、卷曲的菌落,背面呈棕色,后期为酒红色。尤其在“en thrse”状态下形成球形和棒状、单细胞和双细胞的小分生孢子。大多数薄壁大分生孢子顶端圆形,但也可见梭形孢子类型。经常观察到大分生孢子的萌发。将其接种到白色实验小鼠背部皮肤进行实验性感染,在伍德灯下产生了带有亮黄色后期绿色荧光的角质层。简要讨论了昆克毛癣菌的分类学。

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