Rodermund O E, Heymer T, De Vries G A
Mycopathologia. 1975 Jul 30;56(1):31-4. doi: 10.1007/BF00493580.
A vesicular skin lesion which existed since 1 week in the lower part of the leg of a 45-year-old woman appeared to be caused by fungus which was identified as Trichophyton quinckeanum (Zopf) MacLeod & Muende. The patient could not state to have had contact with animals. Peroral administration of griseofulvin and local application of 2% salicyl--5% sulfur--vaseline alternate with tonoftal cream healed the lesion completely. The fast growing fungus produced white, convoluted colonies with a brown, lat er wine-red reverse. Globose and club-shaped, one- and two-celled microconidia were formed especially 'en thrse'. The majority of the thin-walled macroconidia had rounded apices but a fusiform type of spore was also seen. Germination of the macroconidia was frequently observed. Experimental infection into the dorsal skin of white laboratory mouse produced a scutulum with a bright yellow later green fluorescence in Wood's light. The taxonomy of Trichophyton quinckeanum is briefly discussed.
一名45岁女性小腿下部出现水疱性皮肤病变已有1周，似乎是由真菌引起，该真菌被鉴定为昆克毛癣菌（Trichophyton quinckeanum，Zopf）MacLeod & Muende。患者称未与动物接触过。口服灰黄霉素并局部交替使用2%水杨酸-5%硫磺-凡士林和托萘酯乳膏，病变完全愈合。这种生长迅速的真菌产生白色、卷曲的菌落，背面呈棕色，后期为酒红色。尤其在“en thrse”状态下形成球形和棒状、单细胞和双细胞的小分生孢子。大多数薄壁大分生孢子顶端圆形，但也可见梭形孢子类型。经常观察到大分生孢子的萌发。将其接种到白色实验小鼠背部皮肤进行实验性感染，在伍德灯下产生了带有亮黄色后期绿色荧光的角质层。简要讨论了昆克毛癣菌的分类学。
