Rijnders B J, Van Wijngaerden E, Van Eldere J, Peetermans W E
Inwendige geneeskunde, Universitair Ziekenhuis Gasthuisberg Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Clin Microbiol Infect. 2001 Jul;7(7):388-91. doi: 10.1046/j.1198-743x.2001.00272.x.
During a 4-month period we prospectively investigated the frequency of polyclonal catheter infections with Staphylococcus epidermidis. Of each catheter with pure growth of S. epidermidis, six colonies were genotypically analyzed with pulsed-field gel electrophoresis. Two out of 12 patients with catheter infection had a polyclonal infection. Both clones of each catheter had a clearly different antibiotic susceptibility. This study shows that polyclonal catheter infections are not exceptional. Further studies are needed to define the clinical consequences of polyclonal catheter infection.
在4个月的时间里，我们前瞻性地调查了表皮葡萄球菌引起的多克隆导管感染的发生率。对每例表皮葡萄球菌纯培养生长的导管，选取6个菌落进行脉冲场凝胶电泳基因分型分析。12例导管感染患者中有2例发生多克隆感染。每根导管的两个克隆株具有明显不同的抗生素敏感性。本研究表明，多克隆导管感染并不罕见。需要进一步研究来确定多克隆导管感染的临床后果。
