双胞胎中的自杀行为：一项重复研究。
Suicidal behavior in twins: a replication.
作者信息
Roy A, Segal N L
机构信息
Psychiatry Service, Department of Veterans Affairs, VA Healthcare System, East Orange, NJ 07018, USA.
出版信息
J Affect Disord. 2001 Sep;66(1):71-4. doi: 10.1016/s0165-0327(00)00275-5.
OBJECTIVE
Our two previous reports showed that monozygotic (MZ) twins were significantly more concordant for both completed suicide and attempted suicide than dizygotic (DZ) twins. We wished to replicate the finding that MZ co-twins showed greater concordance for suicidal behavior.
METHOD
We collected a new series of 28 twin pairs in which one twin had committed suicide.
RESULTS
We found that 4 of the 13 MZ twin pairs were concordant for suicidal behavior compared with 0 of the 15 DZ twin pairs (P=0.035).
CONCLUSIONS
These data confirm our previous reports that MZ co-twins show greater concordance for suicidal behavior than DZ co-twins, consistent with genetic influence.
目的
我们之前的两份报告显示，同卵（MZ）双胞胎在完成自杀和自杀未遂方面的一致性显著高于异卵（DZ）双胞胎。我们希望重复这一发现，即MZ双胞胎在自杀行为上表现出更高的一致性。
方法
我们收集了新的一组28对双胞胎，其中一对双胞胎自杀。
结果
我们发现，13对MZ双胞胎中有4对在自杀行为上一致，而异卵双胞胎15对中无一对一致（P=0.035）。
结论
这些数据证实了我们之前的报告，即MZ双胞胎在自杀行为上比DZ双胞胎表现出更高的一致性，这与遗传影响一致。
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