Department of Psychology, California State University, Fullerton, CA 92834, USA.
Suicide Life Threat Behav. 2009 Dec;39(6):569-75. doi: 10.1521/suli.2009.39.6.569.
Genetically informative samples can address hereditary and experiential influences on suicide-related behaviors. The frequency of suicide-related behaviors was compared in twins from two survivor groups: (1) those whose co-twins' deaths were suicides (monozygotic [MZ]: n = 47; dizygotic [DZ]: n = 31), and (2) those whose co-twins' deaths were nonsuicides (MZ: n = 347; DZ: n = 170). The frequency of suicide attempts among suicide survivors was significantly higher in MZ than DZ twins, while the frequency of suicide attempts among nonsuicide twin survivors did not differ between MZ and DZ twins. Twin concordance for suicide attempts more likely reflects a genetic predisposition than a behavioral reaction to the loss.
遗传信息样本可以解决与自杀相关行为的遗传和经验影响。在来自两个幸存者群体的双胞胎中比较了与自杀相关行为的发生频率：(1)其双胞胎的死亡是自杀(同卵[MZ]：n=47；异卵[DZ]：n=31)，和(2)其双胞胎的死亡是非自杀(n=347；DZ：n=170)。自杀幸存者的自杀未遂频率在 MZ 双胞胎中显著高于 DZ 双胞胎，而非自杀双胞胎幸存者的自杀未遂频率在 MZ 和 DZ 双胞胎之间没有差异。自杀未遂的双胞胎一致性更可能反映了遗传倾向，而不是对丧失的行为反应。
