Arjomand H, Sokil A B, Arjmand R, Fischer H A, Wolf N M
Department of Medicine, MCP Hahnemann University, Philadelphia, Pennsylvania, USA.
J Invasive Cardiol. 2001 Sep;13(9):647-50.
Primary angioplasty results in higher reperfusion rates than fibrinolysis in patients with acute myocardial infarction (MI). Two recent trials have shown improved rates of reperfusion when a reduced-dose thrombolytic is combined with the platelet glycoprotein IIb/IIIa receptor inhibitor abciximab. We present a case report of acute MI successfully treated with a combination of tirofiban and half-dose alteplase and eventual percutaneous coronary intervention.
在急性心肌梗死(MI)患者中,直接血管成形术比纤维蛋白溶解术能带来更高的再灌注率。最近的两项试验表明,将小剂量溶栓剂与血小板糖蛋白IIb/IIIa受体抑制剂阿昔单抗联合使用时,再灌注率会提高。我们报告一例急性心肌梗死患者成功接受替罗非班与半剂量阿替普酶联合治疗并最终接受经皮冠状动脉介入治疗的病例。