Quality control in molecular genetic testing.

作者信息

Dequeker E, Ramsden S, Grody W W, Stenzel T T, Barton D E

机构信息

European Thematic Network for Cystic Fibrosis and European Molecular Genetics Quality Network (EMQN), Department for Human Genetics, University of Leuven, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.

出版信息

Nat Rev Genet. 2001 Sep;2(9):717-23. doi: 10.1038/35088588.

DNA-based testing for genetic diseases has developed from nothing into a principal part of laboratory medicine over the past 15 years. In the rush to bring these powerful new technologies into medical use, issues of quality have not always been given sufficient attention. Efforts are now being made to assess the quality of the output of genetic testing laboratories, and the results show that there is room for improvement.