Pomerantz D K, Nalbandov A V
Proc Soc Exp Biol Med. 1975 Jun;149(2):413-6. doi: 10.3181/00379727-149-38818.
The androgen content of amniotic fluid, plasma, and gonads from 107 fetal lambs was determined by radioimmunoassay in an attempt to understand the ontogeny of gonadal function. Testosterone (T) was too low to be reliably measured in the amniotic fluid from fetuses of either sex. Ovaries were without T activity at any of the stages of gestation studied. Testicular T-5alpha-dihydrotestosterone (T-DHT) concentration steadily decreased from 1.4/ml near term. It is suggested that nongonadal testosterone production increases during fetal life and that T secretion by the fetal testis may contribute steadily less to the plasma pool of T as gestation proceeds.
通过放射免疫分析法测定了107只胎羊羊水、血浆和性腺中的雄激素含量，以试图了解性腺功能的个体发生过程。无论是雄性还是雌性胎儿的羊水中，睾酮（T）含量都过低，无法可靠地测量。在所研究的任何妊娠阶段，卵巢都没有T活性。睾丸中的T - 5α - 二氢睾酮（T - DHT）浓度在接近足月时从1.4/ml稳步下降。这表明在胎儿期非性腺来源的睾酮生成增加，并且随着妊娠的进展，胎儿睾丸分泌的T对血浆T池的贡献可能会稳步减少。
