Petri M
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rheum Dis Clin North Am. 2001 Aug;27(3):633-42, viii. doi: 10.1016/s0889-857x(05)70225-8.
Antiphospholipid antibody positive patients are at risk for venous and arterial thrombosis. The risk of recurrent thromboembolism is high. Although the standard of care is high-intensity warfarin after a thromboembolic event, some studies indicate that this degree of anticoagulation is not needed. There is an urgent need of clinical trials to address management of thrombosis in antiphospholipid syndrome.
抗磷脂抗体阳性患者有发生静脉和动脉血栓形成的风险。复发性血栓栓塞的风险很高。尽管血栓栓塞事件发生后的标准治疗是使用高强度华法林,但一些研究表明不需要如此程度的抗凝。迫切需要进行临床试验以解决抗磷脂综合征中血栓形成的管理问题。