Klepper L Ia
Med Tekh. 2001 Jul-Aug(4):15-20.
Based on the assumption that tumor tissue consists of normal and radiation-resistant, that the survival of both types of tumor cells may be described by LQ functions and that the count of radiation-resistant cells is in proportion to that of tumor cells, the author has developed a method for calculating the equivalent tumor dose as a function as to irradiated tumor tissue volume for the fixed value of a single dose in the session of radiation. The developed formalism may be used to test the hypothesis that the count of clonogenic and radiation-resistant cells is in proportion to the baseline number of the cells in the tumor tissue.
基于肿瘤组织由正常细胞和抗辐射细胞组成的假设，两种类型肿瘤细胞的存活情况都可用线性二次函数来描述，且抗辐射细胞数量与肿瘤细胞数量成正比，作者开发了一种方法，用于计算在放疗疗程中单次剂量固定时，等效肿瘤剂量与受照射肿瘤组织体积的函数关系。所开发的形式体系可用于检验克隆形成细胞和抗辐射细胞数量与肿瘤组织中细胞基线数量成正比这一假设。
